Wednesday, February 6, 2013

Latest Relocation trends for a stress free move

Relocation was a strenuous process for any newbie looking to move their homes or offices. While people moved their homes and offices, their stress and unease always increased. These stressful times are now just things from the past.

Latest technologies and some of the hottest trends in relocation processes have now made moving simpler than it ever was. Read along to enhance your knowledge about some of these latest relocation ideas that can erase out all your worries and help you enjoy the ?once cumbersome? moving processes.

1.??????Relocation Calculators:

Every time you contemplate a move, you may need vital information about the new location to help you plan your move better. This information may include cost of living comparisons, currency details and your moving expenses. Lack of such information may lead to pricey and reckless moves. If you wish to avoid making such moves, you must use a relocation calculator. Relocation calculators can be easily found on any real estate websites. All you need to do is load the required information, and get all answers to your queries regarding the monetary expenses.

The clear and well laid out analysis by relocation calculators can evade you from most unnecessary trouble and sometimes even convince you to avoid moving. This is mostly because the calculator gives precise estimate on cost of living indices of the new place. You may finally consider not to move if the cost of living standards of the new place are not sufficient for sustaining a comfortable life with your family.

2.??????Acclimatization

If you are scared about taking pets with you while moving to a different climatic zone, it is advisable to acclimatize them to the new environment before making the move. If you?re moving to a tropical place, use heaters at home so that your pets get used to the warmer temperatures. Similarly when you?re taking your pet to colder zones, use air conditioners at home to prepare your pet for the colder climate. You can begin with the acclimatization process at least a month in advance.

Relocation 2

3.??????Moving Cubes

Moving cubes are often known as moving pods or you-pack containers. These are metal containers that you can use for loading your possessions and have them transported safely at your new location. These moving cubes are particularly helpful for people who need professional help only for transportation. These moving cubes are cheaper than hiring moving companies if you can manage the packaging of all your belongings yourself.

4.??????Mobile Apps

The millennial generation is greatly dependent on their smartphones to simplify their lives. Everything appears to be just a few clicks away on your own smartphones. With various interesting and productive apps available, moving has become as easy as walking a mile while listening to music on your IPhone. There are numerous relocation apps available on your mobiles, which can help you hire movers, avail quotes and even organize your move. You can simply avail moving quotes for removals in London , Australia or any other place you?re looking for.

Apps like Cartus, Jump Desktop, Expensify and Twist are popular relocation apps that help you work on all activities related to relocation.
Relocation is no more a daunting task, if you implement some of these technological developments to assist you with the move. The only process that requires your attention after moving is adjustment. Using these developments to help you with the move will only make your move easy, and leave you with more time to adjust at the new location.

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Source: http://www.ebestproducts.com/2013/02/latest-relocation-trends-stress-free-move/

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Monday, February 4, 2013

Growth factor aids stem cell regeneration after radiation damage

Feb. 3, 2013 ? Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.

Reported in the Feb. 3, 2013, issue of the journal Nature Medicine, the researchers explored what had first appeared to be an anomaly among certain genetically modified mice with an abundance of epidermal growth factor in their bone marrow. The mice were protected from radiation damage, and the researchers questioned how this occurred.

"Epidermal growth factor was not known to stimulate hematopoiesis, which is the formation of blood components derived from hematopoietic stem cells," said senior author John Chute, M.D., a professor of medicine and professor of pharmacology and cancer biology at Duke University. "However, our studies demonstrate that the epidermal growth promotes hematopoietic stem cell growth and regeneration after injury."

Hematopoietic stem cells, which constantly churn out new blood and immune cells, are highly sensitive to radiation damage. Protecting these cells or improving their regeneration after injury could benefit patients who are undergoing bone marrow transplantation, plus others who suffer radiation injury from accidental environmental exposures such as the Japanese nuclear disaster in 2011.

The Duke researchers launched their investigation using mice specially bred with deletions of two genes that regulate the death of endothelial cells, which line the inner surface of blood vessels and are thought to regulate the fate of hematopoietic stem cells. Blood vessels and the hematopoietic system in these mice were less damaged when exposed to high doses of radiation, improving their survival.

An analysis of secretions from bone marrow endothelial cells of the protected mice showed that epidermal growth factor (EGF) was significantly elevated -- up to 18-fold higher than what was found in the serum of control mice. The researchers then tested whether EGF could directly spur the growth of stem cells in irradiated bone marrow cultured in the lab. It did, with significant recovery of stem cells capable of repopulating transplanted mice.

Next, the Duke team tried the approach in mice using three different solutions of cells in animals undergoing bone marrow transplants. One group received regular bone marrow cells; a second group got bone marrow cells from donors that had been irradiated and treated with EGF; a third group got bone marrow cells from irradiated donors treated with saline.

The regular bone marrow cells proliferated well and had the highest rate of engraftment in the recipient mice. But mice that were transplanted with the cells from irradiated/EGF-treated donors had 20-fold higher engraftment rate than the third group.

Additional studies showed that EGF improved survival from a lethal radiation exposure, with 93 percent of mice surviving the radiation dose if they subsequently received treatment with EGF, compared to 53 percent surviving after treatment with a saline solution.

Chute said it appears that EGF works by repressing a protein called PUMA that normally triggers stem cell death following radiation exposure.

"We are just beginning to understand the mechanisms through which EGF promotes stem cell regeneration after radiation injury," Chute said. "This study suggests that EGF might have potential to accelerate the recovery of the blood system in patients treated with chemotherapy or radiation."

In addition to Chute, study authors include Phuong L. Doan, Heather A. Himburg, Katherine Helms, J. Lauren Russell, Emma Fixsen, Mamle Quarmyne, Jeffrey R. Harris, Divino Deoliviera, Julie M. Sullivan, Nelson J. Chao and David G. Kirsch.

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The above story is reprinted from materials provided by Duke University Medical Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Phuong L Doan, Heather A Himburg, Katherine Helms, J Lauren Russell, Emma Fixsen, Mamle Quarmyne, Jeffrey R Harris, Divino Deoliviera, Julie M Sullivan, Nelson J Chao, David G Kirsch & John P Chute. Epidermal growth factor regulates hematopoietic regeneration after radiation injury. Nature Medicine, 03 February 2013 DOI: 10.1038/nm.3070

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/rI545Mcsylo/130203145556.htm

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Will more research on violent video games unearth answers, or just ...

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Although it is becoming commonplace for politicians and others to blame violent video games for all the recent shooting tragedies, the truth is that there has not been any conclusive evidence linking the two. In fact, researchers like Dr. Kevin Williams think there is more to it.

The fallout from the tragic shooting rampage in Newtown, Connecticut will be with us for years. It has sparked several debates about the state of our society, uniting a large percentage of the of the nation against loose gun laws, while others seek to place the blame elsewhere. That includes a new surge of attention focusing on violent entertainment, with video games drawing a big bulls eye thanks in part to the National Rifle Association blaming games?(along with movies, music, natural disasters, celebrities, foreign aide, and President Obama)?for tragic events like the Sandy Hook Elementary shooting. And yet despite politicians like Rep. Diane Franklin (D-CA) stating that violent games cause diagnosable mental health conditions and Senator Lamar Alexander (R-TN)?claiming that video games are a bigger threat than guns, there?s no evidence linking violent games in any such capacity.

?Some studies have claimed they are measuring violence but I?m not sure I necessarily agree with their interpretation,? said Dr. Kevin D. Williams, Associate Professor of Communication at Mississippi State University. ?They may have a participant buzz another unfamiliar person with a loud blast of noise. They may have a participant fill out a questionnaire stating how that participant would punish someone in a hypothetical situation. Let?s be honest. At the heart of the situation is fear that a game player after playing a violent game would physically assault or perhaps kill another person. Noise blasts to a complete stranger or writing down a punishment to a fake situation doesn?t seem like a realistic measure of true violence.?

Williams is a leading expert in the field of the effects of video games. In 2006 he was honored with the Broadcast Education Association?s Best Doctoral Dissertation Award, in which he claimed that??The research suggests that frustration with game play may be a more important factor in inspiring violence than merely viewing graphic violence in the games,? Williams said.?

While there have been a lot of individual research studies done throughout the U.S. and around the globe involving video games and violence, there has thus far been no conclusive evidence linking the two. That?s one of the reasons Vice President Joseph Biden recently met with video game publishers and developers in Washington, D.C. in his effort to explore this topic. One issue with many politicians, including Biden, is that they?re very old, and certainly not gamers.

?I think a lot of the older legislators thought we had thoroughly explored the impact violent media had on viewers,? said Williams. ?In the past few decades there had been congressionally lead studies on the impact of violent movies and television on viewers. I believe those politicians had the misperception that games were just an extension of that. Games are much different in that they fully involve the player. The player in part generates the narrative and is responsible for what happens on the screen. It?s a different medium than movies or television and deserves to be studied and treated as such. I hope that younger politicians realize this. I also hope they put their money where their mouth is. Watching the Sunday morning talk shows, I hear a lot of politicians who want to blame the games more than the guns. I understand their argument, but are they willing to really fund and do the work now that they?ve pointed out the gorilla in the room??

But even more research isn?t likely to quell the debate. There have been plenty of studies over the years, but there are also those who are pushing their own agendas even within this research.

?As scientists we like to put these statistical limits on things as if one hundredth of a decimal point makes a concern valid or not,? said Williams. ?We?re too caught up in our own egos to see that perspective matters. Readers of violence research should be cautious and come to know not only the research being presented but the researcher as well. There are a lot of big personalities in this field. Some have staked their professional career on proving there is an effect. Some have staked their career on countering others? claims. Up and coming researchers like myself can get caught in the crossfire, having their work validated or invalidated because of who they quoted as opposed to the design of their research.?

One good thing that can come from the current media exposure around violent games is funding for more research. With the upcoming release of Rockstar Games? Grand Theft Auto V, there?s sure to be plenty of media attention around violent games throughout this spring, at least. Researchers believe more has to be done to explore violence in games, and that sentiment is shared by President Obama.

?Most of the video game studies are single exposure experiments,? said Williams. ?Participants play a game once and are then measured. Any effect they experience wears off quickly. We need more experiments that systematically investigate long term repeated exposure. Unfortunately, there is a lack of funds to do such experiments at most universities.?

Williams? research has focused on the moderators of violent video games. While he?s interested in the effects of violent video games on players, he?s more interested on the aspects of video games that could influence a violence effect. He most recently explored the impact Wii motion control games have on hostility. He found that the additional connection the gamer has with the avatar through motion controls does increase the hostility effect, but that?s different than enticing someone to go out and commit violent acts.

?I look at hostility because I feel we can accurately measure that and we also know that hostility is related to acts of violence,? said Williams. ?But it does not mean that hostility always leads to real violence. Overall, we see that hostility effects are small and short lived.?

One thing that has come up in the current debate is the role parents play in all of this. Gamers who are of age have a First Amendment right to play games and watch entertainment that they want. Gamers who don?t have children don?t want to be penalized for parents who don?t want to take an active role in their kids? lives.

?Parents play the most important role,? said Williams. ?We know from past research that the most likely predictor of whether someone is going to become violent later in life is their parents? view of violence. Was it a violent home? Was there domestic violence? Did the parents exemplify that violence solves problems? We all have that wall built up inside us, that wall that tells us to not take a swing at somebody when they treat you badly. That wall is built by religion and social rules, but most importantly, by parents. Can you know what media your child is engaging with at all times? No, media saturates our lives too completely, but parents must be vigilant as to knowing what media their children are consuming. Certainly there is no reason why a parent should not be investigating what games their child is asking them to buy. Popular games are not only filled with violence but also with sexuality and adult language. Retailers must also do a better job of restricting sales to minors when the games are not age appropriate. I know some businesses which do a wonderful job, but it needs to be more consistent across the nation.?

The good news for gamers who are worried about the political maelstrom is that not even The Terminator could ban the sale of ?offensively violent? video games to minors in California. Governor Arnold Schwarzenegger took his case against the Entertainment Software Association all the way to the Supreme Court and lost. Rep. Jim Matheson recently introduced a bill that would make it unlawful to sell or rent violent or Mature-rated video games to minors, making it punishable by a fine of up to $5,000. However, this bill is likely to face an uphill battle. And every effort to date in states across the country that has tried to fight the free speech games enjoy has failed. It?s likely there will be new research, and depending on those findings, the future of this debate could change.

Source: http://www.digitaltrends.com/gaming/will-more-research-on-violent-video-games-unearth-answers-or-just-more-questions/

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Friday, February 1, 2013

HBO Go reportedly coming to Apple TV

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Apple (AAPL) is said to be in negotiations with Time Warner (TWX) to offer an HBO Go application on Apple TV by mid-2013, according to sources speaking to Bloomberg. The set-top box already carries services from Netflix (NFLX) and Hulu, and the addition of HBO Go could help Apple boost sales of the device. The service allows HBO subscribers to stream original TV shows and movies on the Web and through variety of devices such as Android and iOS smartphones and tablets, TVs, Blu-ray players, Roku boxes and gaming consoles.

[More from BGR: GS: Ignore the chatter, BlackBerry rebound is coming]

Peter Kafka at AllThingsD brought up a good point: why hasn?t Apple opened up its Apple TV platform to everyone? The company?s iPhones and iPads have flourished due to the large selection of third-party apps and games found in the App Store. While the inclusion of an HBO Go app would be nice, the Apple TV needs a full-blown App Store to drive the nail into the coffin of other streaming devices.

[More from BGR: Here comes the PlayStation 4: Sony announces February 20th PlayStation event [video]]

Apple TV currently comes preloaded with a total of nine different apps, a paltry number compared to Roku and Google TV.

This article was originally published on BGR.com

Source: http://news.yahoo.com/hbo-reportedly-coming-apple-tv-162516348.html

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Today in History

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Source: http://news.yahoo.com/today-history-050206767.html

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Feds: $13.6M in phony sports goods confiscated

(AP) ? Investigators have confiscated more than $13.6 million worth of phony sports merchandise over the past five months and expect to seize more in New Orleans during Super Bowl week, a federal law-enforcement official said Thursday.

U.S. Immigration and Customs Enforcement Director John Morton said authorities also have shut down more than 300 websites selling counterfeit goods as part of an enforcement effort dubbed "Operation Red Zone."

The operation targeted international shipments of jerseys, hats and other souvenirs entering the U.S. for sale by stores, flea markets and street vendors.

More than 160,000 counterfeit items, mostly purporting to be official Super Bowl and other NFL merchandise, were seized during the operation. A total of 23 people have been arrested on related charges since September 2012.

"We attacked the counterfeiters at every point along the criminal supply chain," Morton said during a press briefing in New Orleans.

Morton said agents also were in the city this week to crack down on the sale of counterfeit merchandise before Sunday's Super Bowl between the San Francisco 49ers and Baltimore Ravens.

"This just takes good old-fashioned police work, people getting out on the streets," he said.

This is the fifth consecutive year that federal authorities have launched a similar operation to crack down on the sale of counterfeit sports goods. Roughly $5.1 million in goods were seized during the previous one, Morton said.

"This is the largest number we've ever seized," Morton said of the $13.6 million.

Morton said copycat websites selling bogus merchandise have become increasingly sophisticated in their efforts to dupe customers into believing they're purchasing licensed, official sportswear.

"The prices are not ridiculously low. They're just discounted enough to fool the consumer," he added.

Anastasia Danias, the NFL's vice president for legal affairs, said fans also need to be wary of buying counterfeit Super Bowl tickets from "any suspicious sources."

"We learn of hundreds of fans every year who travel to the host city with the hope of watching their team play in the Super Bowl game only to be turned away at the gate, having bought counterfeit tickets or tickets that were reported lost or stolen," she said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-01-31-FBN-Super-Bowl-Merchandise/id-d211f8e7404c4e4fbd252c3bc35cbc80

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